Rx Outreach is a nonprofit, mail-order pharmacy that provides over 1000 affordable medication strengths to people across the United States and Major US Territories. Rx Outreach was a program originally developed in 2004 as a subsidiary of Express Scripts. In 2010, Express Scripts spun off Rx Outreach to be a standalone, charitable organization to improve access to prescription medications for uninsured and underinsured people. We have provided prescription medications to over 500,000 patients.

Since 2010, Rx Outreach has been committed to providing safe, affordable medications to patients across the nation. All of our medications are FDA-approved and sourced directly from pharmaceutical manufacturers. We are regulated by the Federal Drug Enforcement Agency and licensed by the Bureau of Narcotics and Dangerous Drugs. Additionally, we maintain the necessary licensing to deliver FDA-approved medications.

All prescriptions are filled by licensed pharmacists at our pharmacy located in the St. Louis area. We ensure your prescriptions are mailed in secure, nondescript packaging to any address you specify, with all packages being trackable.

Rx Outreach is proud to be accredited by several esteemed organizations: the National Association of Boards of Pharmacy as an Accredited Digital Pharmacy, the Better Business Bureau as an Accredited Charity, and GuideStar as a Platinum Level charity, which is the highest rating possible.

Our commitment to excellence has been recognized nationally, with Rx Outreach being listed among the "Best Online Pharmacies" by Forbes in 2022, 2023, and 2024, and by Money Magazine in 2020 and 2021.

While most medications from Rx Outreach are not free, our status as a nonprofit organization enables us to offer prices significantly lower than those at retail pharmacies. Additionally, through various partnerships, we offer a selection of medications for free. To find these free medications, visit the "Find Your Medication" tab on our website and type "$0" in the search bar. You can also sign up for our newsletter by clicking on the button for "eNews Sign Up” to learn about the latest programs and price changes offered by Rx Outreach.

Yes, many of our patients find our medication prices are less than their co-pays when visiting a traditional pharmacy. Rx Outreach does not accept insurance (including Medicare), so all costs are out-of-pocket.

Rx Outreach provides affordable medications and delivers them right to your door. Our program is simple with transparent prices, no hassle with coupons, and convenient features such as text refills. Our pharmacy also provides high-quality service and dispensing accuracy due to the level of automation used in dispensing your prescription.

To contact Rx Outreach, please call 314-222-0472 or 800-769-3880. Our Patient Contact Center is open 7 a.m. – 6 p.m. CST Monday through Thursday and 7 a.m. – 5:30 p.m. CST. Voicemails will be responded to within two business days.

No, there is not a discount card needed to utilize Rx Outreach, and you will not receive or need to maintain a card.

Sign up for our eNews to stay up to date on our medications, pricing changes, and new programs. Click the "eNews Sign up” button at the top of each of our web pages and enter your email.

We add medication based on community needs and our ability to secure competitive pricing. If we do not have the medication you need, please fill out the form here.

We recommend Needy Meds (https://www.needymeds.org) to find Patient Assistance Programs and discounted medication programs.

To open an account, visit our login page (https://portal.rxoutreach.org/register). You can also call us at 314-222-0472 or simply have your prescription sent to us.

If you know Rx Outreach carries your medication, your doctor can prescribe your medication to Rx Outreach electronically (Surescripts network under NCPDP ID 2635855) or by fax (1-800-875-6591). Some patients download and bring our Medication List by Disease State to their doctor to see if a less expensive alternative is available at Rx Outreach.

Please call us to add a credit or debit card to your account. We will not charge your card without authorization. If you set up pay authorization, we will text you when it is time for a refill. You can reply “Yes” to this text, and we’ll process your order and send your medication to you.

You can mail your check or money order to:

Rx Outreach
3171 Riverport Tech Center Drive
Maryland Heights, MO 63043

Please call us at 314-222-0472 to add this feature to your account. If you have a credit or debit card on file and receive texts, we will text you when it is time for a refill. You can reply “Yes” to this text, and we’ll process the payment for your order and send your medication to you.

Although different states have different regulations regarding controlled medications, you generally need a form of identification if you see “(CS)” following the name of your medication on our Medication List. You can upload a copy of your government-issued photo ID (for example, a driver’s license, state ID, or passport) through the Patient Portal under the settings menu. We only need the front side of your license.

You can manage your account at https://portal.rxoutreach.org/login. If you cannot access your account, be sure to use the same email address as when you opened your account. You can reset the password from that page.

Refills may be requested through the patient portal, through text messaging, or by phone if you are using a credit card.

To request a refill of your medication(s) online, log into the patient portal, select the Refill button on your patient page, enter your information in all the appropriate fields, and submit. Your order will be processed within 48 hours.

If you wish to call to refill your prescription, please call customer service at 314-222-0472.

If you would like to refill by text messaging, please let us know so that this feature is active on your account. We’ll text you and ask if you’d like a refill. Reply “Yes” and the automated refill process will begin.

If you have no refills left on your prescription, please request your doctor send a new prescription.

You can check your refills in the Patient Portal. You will also receive a Refill Reminder call or text reminder approximately two weeks before your medication runs out if you opt-in to receive text message alerts. To make sure you do not have a lapse in your medication, please take action when you receive these notifications.

You can check the status of your order through the Patient Portal. Log in to your account to view the status of all of your prescription orders. Please note that shipment status updates may take up to 24 hours to appear after your order has shipped. If you have additional questions about your order, please call us at 1-314-222-0472 or 1-800-769-3880.

If texting is enabled on your account, when your order is processed, you will receive a text with the tracking number. Shipment status updates may not be available for up to 24 hours after the order ships.

You can sign up for texting when you first enroll through the Patient Portal or by calling and letting our staff know you’d like to enable that feature on your account. Once you have created an account in the patient portal, you will need to call us to add the texting feature.

Most of our medications and diabetic supplies are dispatched via major shipping carriers and include delivery confirmation. Controlled substances are sent through USPS First Class and require a signature upon delivery.

Once we receive all necessary items to process your prescription—including the prescription itself, payment, and any required ID—your prescription will be validated and shipped. It will arrive within 3-6 business days under our free standard shipping, which is included in the price of your medication. This shipping method is ideal for long-term medications, such as those for high blood pressure or diabetes, including supplies.

For select controlled medications, delivery may be faster. Expedited shipping is available for an additional fee, though it cannot be applied to PO Box addresses or certain locations outside the continental U.S., such as Puerto Rico, Hawaii, and Alaska. Expedited delivery times and fees vary based on the package's weight and destination. For more details or to arrange expedited shipping, please contact customer service at 314-222-0472 or 800-769-3880.

*Overnight SATURDAY ($70) is only available on packages shipping out on Fridays and must be approved by a supervisor. Not all addresses are eligible for Saturday delivery.

If your prescription does not reach you in the initial shipment period (6-10 days), please call customer service immediately at 1-314-222-0472. Don’t worry, your Rx Outreach prescriptions are mailed in a secure, nondescript package and tracked. We cannot provide refunds or replacements after 30 days.  We are unable to accept returned medications, even if they are unopened.

For the most up-to-date list of medications and prices, view the list on our website under the Find Your Medication tab. You may search by medication or sort the list by column.

Rx Outreach primarily offers generic drugs, which are a chemically equivalent, lower-cost version of brand-name drugs. A brand-name drug and its generic equivalent are required by the FDA to have the same active ingredient, dosage, safety, strength, usage directions, quality, performance, and intended use. At Rx Outreach, you’ll find the same quality medications that you’re used to or the generic equivalent for less, delivered to your door.