Rx Outreach is a non-profit, mail-order pharmacy that provides over 400 affordable medications to people in need. We have provided prescription medications to over 500,000 patients. Rx Outreach was a program that was developed by a subsidiary of Express Scripts, Inc. in 2004. In 2010, Express Scripts spun off Rx Outreach to be a stand-alone, charitable organization in order to improve access to prescription medicines for low-income, uninsured patients.

Rx Outreach is available to individuals and families whose income is at or below 300% of the Federal Poverty Level. For a single person, annual income cannot exceed $33,510; a family of four may have an annual household income up to $69,150. Please refer to the Eligibility Tab on the website.

For the most up-to-date drug list and administrative fees, view the list on our website under the Medications Tab. You may search by medication or sort the list by column.

Rx Outreach offers over 400 medications to help you treat chronic health conditions. Take the Rx Outreach Medication list to your healthcare provider and see if there is another medication in that therapeutic category that is available through the Rx Outreach Program.

Rx Outreach provides affordable medications for people in need. Many of the medications on our program allow for a substantial savings over your local retail pharmacy cost. Last year alone, we saved our patients over $40 million. Mail order pharmacies also provide high-quality service and dispensing accuracy due to the level of automation used in dispensing your prescription. Lastly, it is convenient to get your medications delivered right to your door.

Each year we serve over 60,000. Rx Outreach has served more than 500,000 patients since its introduction.

You may enroll online! Go to the Application Tab, click on the Apply Now button and simply enter the data in the appropriate fields, click submit, and your enrollment is complete!
You may also download an application from the website. Complete the simple one-page enrollment form, include your valid prescription and payment, and mail to:
Rx Outreach
P.O. Box 66536
St. Louis, MO 63166-6536

Enrollment in the Rx Outreach Program is valid for one year. At your one-year anniversary you will be required to re-enroll. To re-enroll, you will be asked to attest that your annual household income still falls within the current guidelines of the program.

When you enroll, you are not required to submit any documentation verifying your income or to provide any other form of identification. Your signature on the application is attesting that the information you are providing is complete and accurate.
If you are ordering any of our nine controlled substances, you will be required to provide a copy of your photo ID (for example, a driver’s license or state ID card) AND a copy of your Social Security Card or Green Card (or a copy of your paystub or latest income tax form).

There is no cost to enroll in Rx Outreach. There are no monthly or annual membership fees either. You just pay a small administrative fee for each prescription you order.

Yes. Once you have been enrolled in the program you may transfer your prescriptions to Rx Outreach. Your prescriptions must have enough refills for a 90-day supply to be able to complete the transfer. Please call customer service at 800-769-3880 to request your transfer and to provide payment information.

Once the application is approved and your prescription validated; your medication will be shipped to arrive in 10 to 14 days. Mail order programs are intended for drugs that you take over a long period of time, such as high blood pressure medication, diabetes medications and supplies, etc.

Yes. Even patients who are eligible for Medicare Part D can realize a savings when using the Rx Outreach Program, specifically when they reach the “donut hole”.

Along with your completed application, you must submit a valid prescription for each medication that you want to receive through the program and your payment (check, money order, credit card information).

If you are using a credit card (credit card information was provided during the online enrollment), have your physician or healthcare provider fax your prescription to 1-800-875-6591.


If you are mailing in your prescription and/or payment, please make sure that your prescription(s) include your first and last name and two of the following items:
1. Shipping address
2. Date of Birth
3. Social Security Number
Mail your information to:
Rx Outreach, Inc.
P.O. Box 66536
St. Louis, MO 63166-6536

If your enrollment has been denied because your annual income does not meet the program requirements; you may appeal by submitting the following documents:
1. Completed Application
2. Proof of Annual Income
3. Narrative explaining the reason for the appeal, i.e. excessive medical expenses
4. Documentation supporting the narrative

The fee covers the cost of filling the prescription, packing the medicines securely, and delivering them to the patient’s home or address of choice. It is important to sustain the program over the long term so that participants can count on the program being available well into the future.

The majority of our medications and all diabetic supplies are shipped through USPS with delivery confirmation. Controlled substances ship via USPS first class with signature confirmation. You may also request that your shipment be expedited.

You may request expedited shipping via FedEx for an additional fee. Fees are based on the weight and destination of the package. Please call customer service at 1-800-769-3880 for more information or to request an expedited shipment.

Yes. Rx Outreach medications are filled at our St. Louis pharmacy by licensed pharmacists. We mail the prescriptions in a secure package to any address of your choice.

All Rx Outreach prescriptions are mailed in a secure, non-descript package. If a prescription does not reach you in the initial shipment, please call 1-800-769-3880.

You are able to check the status of your order directly online. Log in to your account to view the status of all of your prescription orders. If you have additional questions about your order, please call us toll-free at 1-800-769-3880, Monday through Friday, 7 a.m. to 5:30 p.m. Central Time.

A pharmacist is also available to answer questions about your medicine. Please call customer service at 1-800-769-3880 and request to speak with a pharmacist.

You will receive a Refill Reminder letter approximately 3 weeks prior to your medication running out. In order to make sure you do not have a lapse in your medication, please take action when you receive this letter.
If the prescription we have on file for you does not have any refills remaining, you will receive a Renewal Reminder letter. Please take this letter to your healthcare provider in order to have a new prescription written for your medication(s).

Refills may be requested through the website or by phone if you are using a credit card. To request a refill of your medication(s) online, select the Submit Online Refill icon on the home page, enter your information in all the appropriate fields including the prescription numbers for the medication(s) you wish to refill, click submit…your order will be processed in 48 hours.
If you wish to mail in your refill order, go to the Forms tab and select the Refill Form, print the form and complete it. Mail the completed form and payment to:
Rx Outreach
P.O. Box 66536
St. Louis, MO 63166-6536

All of our medications are FDA approved and directly supplied by either the pharmaceutical manufacturer or a recognized national drug wholesaler. All of our suppliers are licensed by the State of Missouri – a requirement of the Missouri Board of Pharmacy. Also, all prescriptions that are provided through Rx Outreach are verified filled by U.S. licensed pharmacists.

Rx Outreach offers primarily generic drugs, which are a chemically equivalent, lower-cost version of brand-name drugs. A brand-name drug and its generic equivalent are required by the FDA to have the same active ingredient, dosage, safety, strength, usage directions, quality, performance and intended use. At Rx Outreach, you’ll find the same quality medications that you’re used to or the generic equivalent for less, delivered to your door.  

Medication from Rx Outreach is not free, however, as a non-profit organization; you pay an affordable price for your medication. There are no additional enrollment fees, membership fees, or standard shipping fees.  Medications are significantly less expensive than retail pharmacies.  

Rx Outreach is a fully accredited pharmacy located in St. Louis, Missouri. All of our medications are FDA approved and supplied directly by the pharmaceutical manufacturers. We are regulated by the Federal Drug Enforcement Agency, licensed by the Bureau of Narcotics and Dangerous Drugs and maintain licensing to deliver FDA approved medications. Rx Outreach is accredited by the following:

  • National Association of Boards of Pharmacy VIPPS accreditation (“Verified Internet Pharmacy Practice Sites”)
  • The Better Business Bureau (Accredited Charity)
  • GuideStar (Platinum Level, the highest possible rating)

Look here for the most up-to-date medication list and costs. You can search by medication or condition. If you aren’t sure if your medication is available, call 800-769-3880 to speak with one of our Patient Care Advocates.  

Rx Outreach offers more than 1,000 medication strengths to help you treat chronic conditions. If you don’t see your medication on our list, call 800-769-3880 to speak with one of our Patient Care Advocates. You can also take the Rx Outreach medication list to your doctor and see if there is an alternative medication that might work for you.  

Eligibility is based on income: People qualify with annual income of $37,470 or less for a single person, $50,730 or less for family of two, $63,990 or less for a family of three, $77,250 or less for family of four.  

There are no coupons or cards required nor are there additional or hidden fees such as membership fees or shipping fees.  We believe in transparent pricing. At Rx Outreach, the price you see is the price you actually pay!  

Please call 800-769-3880. Our Patient Contact Center is open 7:00am – 5:30pm CST Monday through Friday. Voicemails will be responded to within two business days.  

At this time, insulin is not available from Rx Outreach, however, we do carry Insulin Syringes, Blood Glucose Monitors and Strips, Lancets, and some medications that help control blood sugar for diabetes (Glipizide Tablets, Glimepiride Tablets, etc.).  

We get asked this question so often that we decided to add it to the FAQ’s! Rx Outreach’s mission is to provide affordable medication for people in need. Our vision is a world where every person has access to the medications they need. As the nation’s largest nonprofit pharmacy, Rx Outreach truly understands and appreciates the value of your dollar. We also understand that whether you are uninsured, under-insured, or insured the cost of medication can significantly impact your budget for life’s other necessities.